Author

Xavier Fernàndez‐Busquets

Barcelona Institute of Science and TechnologyORCID 0000-0002-4622-9631Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:non-human primate· 1

Frequent Co-Authors

Cédric S. AsensioiD· 1 shared Dario AnselmettiiD· 1 shared Fabian RupertiiD· 1 shared M. Sabrina PankeyiD· 1 shared Monika DzieciątkowskaiD· 1 shared Oriol BárcenasiD· 1 shared Scott A. NicholsiD· 1 shared Valentín IglesiasiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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1 shared paperBiochemistry

Cédric S. AsensioORCID

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2 papers

Recent·Most cited

Liquid-liquid phase separation (LLPS) as a sensing and adaptation mechanism: An evidence-based hypothesis on AP2 transcription factors in the malaria parasite

Valentín Iglesias, Yunuen Avalos‐Padilla, Oriol Bárcenas, Xavier Fernàndez‐Busquets

The paper proposes that PfAP2 transcription factors in Plasmodium falciparum use liquid-liquid phase separation (LLPS) to sense environmental changes and regulate gene responses, suggesting LLPS as a therapeutic target.

bioRxiv · Dec 12, 2025 · PreprintBioinformatics

Proteomic analysis of the Aggregation Factor from the sponge Clathria (Microciona) prolifera suggests an ancient protein domain toolkit for allorecognition in animals

Fabian Ruperti, Monika Dzieciątkowska, M. Sabrina Pankey, Cédric S. Asensio, Dario Anselmetti, Xavier Fernàndez‐Busquets, Scott A. Nichols

The paper uses proteomics to identify AF components in sponges and finds conserved domains suggesting an ancient toolkit for cell adhesion and allorecognition.

Proceedings of the National Academy of Sciences · Dec 18, 2024Peer-reviewedBiochemistry