Author

Xena Giada Pappalardo

University of CataniaORCID 0000-0002-4640-6677Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Angela Anna MessinaiD· 3 shared Federica ZinghirinoiD· 3 shared Francesca GuarinoiD· 3 shared Vito De PintoiD· 3 shared Angela OstuniiD· 1 shared Daniela Luciano· 1 shared Faustino BisacciaiD· 1 shared François IchasiD· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMolecular Biology

Angela Anna MessinaORCID

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3 papers

Recent·Most cited

Human VDAC pseudogenes: an emerging role for VDAC1P8 pseudogene in acute myeloid leukemia

Xena Giada Pappalardo, Pierpaolo Risiglione, Federica Zinghirino, Angela Ostuni, Daniela Luciano, Faustino Bisaccia, Vito De Pinto, Francesca Guarino, Angela Anna Messina

The paper investigates VDAC pseudogenes, showing VDAC1P8 is over-expressed in AML and correlated with reduced VDAC1 expression.

bioRxiv · Jan 20, 2023 · PreprintGenomics

The secret of VDAC isoforms is in their gene regulation? Characterization of human VDAC genes expression profile, promoter activity, and transcriptional regulators.

Federica Zinghirino, Xena Giada Pappalardo, Angela Anna Messina, Francesca Guarino, Vito De Pinto

The paper analyzes the expression profiles, promoter activity, and transcriptional regulators of human VDAC1-3 genes, revealing distinct regulatory mechanisms and biological functions for each isoform.

International Journal of Molecular Sciences · Oct 7, 2020Peer-reviewedMolecular Biology

NRF-1 and HIF-1α modulate activity of human VDAC1 gene promoter during starvation and hypoxia in HeLa cells

Francesca Guarino, Federica Zinghirino, Lia Mela, Xena Giada Pappalardo, François Ichas, Vito De Pinto, Angela Anna Messina

The paper investigates how NRF-1 and HIF-1α regulate VDAC1 promoter activity under starvation and hypoxia in HeLa cells, showing increased transcription under stress conditions.

Biochimica et Biophysica Acta (BBA) - Bioenergetics · Aug 15, 2020Peer-reviewedMolecular Biology