Angela Anna Messina

ERK1/2-dependent TSPO overactivation associates with the loss of mitophagy and mitochondrial respiration in ALS

The paper shows that TSPO overactivation, driven by ERK1/2 pathway activation, is linked to impaired mitophagy and reduced mitochondrial respiration in a mouse model of ALS.

Human VDAC pseudogenes: an emerging role for VDAC1P8 pseudogene in acute myeloid leukemia

The paper investigates VDAC pseudogenes, showing VDAC1P8 is over-expressed in AML and correlated with reduced VDAC1 expression.

Small Extracellular Vesicles Secreted by Region-specific Astrocytes Ameliorate the Mitochondrial Function in a Cellular Model of Parkinson's Disease

The paper investigates the neuroprotective effects of small extracellular vesicles from region-specific astrocytes in Parkinson's disease, showing they improve mitochondrial function.

The secret of VDAC isoforms is in their gene regulation? Characterization of human VDAC genes expression profile, promoter activity, and transcriptional regulators.

The paper analyzes the expression profiles, promoter activity, and transcriptional regulators of human VDAC1-3 genes, revealing distinct regulatory mechanisms and biological functions for each isoform.

NRF-1 and HIF-1α modulate activity of human VDAC1 gene promoter during starvation and hypoxia in HeLa cells

The paper investigates how NRF-1 and HIF-1α regulate VDAC1 promoter activity under starvation and hypoxia in HeLa cells, showing increased transcription under stress conditions.