Author

Pierpaolo Risiglione

University of CataniaORCID 0000-0002-6832-3573Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Angela Anna MessinaiD· 3 shared Andrea MagrìiD· 2 shared Francesca GuarinoiD· 2 shared Angela OstuniiD· 1 shared Antonella CaccamoiD· 1 shared Bianca MarchettiiD· 1 shared Carlos A. P. BastosiD· 1 shared Cataldo TiroloiD· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Angela Anna MessinaORCID

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3 papers

Recent·Most cited

ERK1/2-dependent TSPO overactivation associates with the loss of mitophagy and mitochondrial respiration in ALS

Andrea Magrì, Cristiana Lucia Rita Lipari, Pierpaolo Risiglione, Stefania Zimbone, Francesca Guarino, Antonella Caccamo, Angela Anna Messina

The paper shows that TSPO overactivation, driven by ERK1/2 pathway activation, is linked to impaired mitophagy and reduced mitochondrial respiration in a mouse model of ALS.

Cell Death and Disease · Feb 15, 2023Peer-reviewedNeuroscience

Human VDAC pseudogenes: an emerging role for VDAC1P8 pseudogene in acute myeloid leukemia

Xena Giada Pappalardo, Pierpaolo Risiglione, Federica Zinghirino, Angela Ostuni, Daniela Luciano, Faustino Bisaccia, Vito De Pinto, Francesca Guarino, Angela Anna Messina

The paper investigates VDAC pseudogenes, showing VDAC1P8 is over-expressed in AML and correlated with reduced VDAC1 expression.

bioRxiv · Jan 20, 2023 · PreprintGenomics

Small Extracellular Vesicles Secreted by Region-specific Astrocytes Ameliorate the Mitochondrial Function in a Cellular Model of Parkinson's Disease

Loredana Leggio, Francesca L’Episcopo, Andrea Magrì, María José Ulloa-Navas, Greta Paternò, Silvia Vivarelli, Carlos A. P. Bastos, Cataldo Tirolo, Nunzio Testa, Salvatore Caniglia, Pierpaolo Risiglione, Fabrizio Pappalardo, Nuno Faria, Luca Peruzzotti‐Jametti, Stefano Pluchino, , Nunzio Iraci

The paper investigates the neuroprotective effects of small extracellular vesicles from region-specific astrocytes in Parkinson's disease, showing they improve mitochondrial function.

bioRxiv · Apr 23, 2021 · PreprintNeuroscience