Author

Vito De Pinto

University of CataniaORCID 0000-0001-5513-2906Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Angela Anna MessinaiD· 3 shared Federica ZinghirinoiD· 3 shared Francesca GuarinoiD· 3 shared Xena Giada PappalardoiD· 3 shared Angela OstuniiD· 1 shared Daniela Luciano· 1 shared Faustino BisacciaiD· 1 shared François IchasiD· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMolecular Biology

Angela Anna MessinaORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintJan 20, 2023

Human VDAC pseudogenes: an emerging role for VDAC1P8 pseudogene in acute myeloid leukemia

Xena Giada Pappalardo, Pierpaolo Risiglione, Federica Zinghirino…·Angela Anna Messina

The paper investigates VDAC pseudogenes, showing VDAC1P8 is over-expressed in AML and correlated with reduced VDAC1 expression.

DOI 10.1101/2023.01.20.524880

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologyInternational Journal of Molecular SciencesPeer-reviewedOct 7, 2020

The secret of VDAC isoforms is in their gene regulation? Characterization of human VDAC genes expression profile, promoter activity, and transcriptional regulators.

Federica Zinghirino, Xena Giada Pappalardo, Angela Anna Messina…·Vito De Pinto

The paper analyzes the expression profiles, promoter activity, and transcriptional regulators of human VDAC1-3 genes, revealing distinct regulatory mechanisms and biological functions for each isoform.

33 citations

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologyBiochimica et Biophysica Acta (BBA) - BioenergeticsPeer-reviewedAug 15, 2020

NRF-1 and HIF-1α modulate activity of human VDAC1 gene promoter during starvation and hypoxia in HeLa cells

Francesca Guarino, Federica Zinghirino, Lia Mela…·Angela Anna Messina

The paper investigates how NRF-1 and HIF-1α regulate VDAC1 promoter activity under starvation and hypoxia in HeLa cells, showing increased transcription under stress conditions.

34 citations

humanstatistical model

𝕏 PostBluesky