Author

Yuyan Li

Academy of Military Medical SciencesORCID 0000-0002-4640-8330Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:matrix factorization· 1 Assay:multiome· 1

Frequent Co-Authors

Aiping WuiD· 1 shared Alexander KaneiD· 1 shared Bolun LiiD· 1 shared Cheng‐Feng QiniD· 1 shared Christopher Ian AmosiD· 1 shared Cong WangiD· 1 shared Erping LongiD· 1 shared Eun Young KimiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Aiping WuORCID

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2 papers

Recent·Most cited

Viral protease-Initiated Pyroptosis Activator mRNA therapy as a Universal Antiviral Strategy

Lin Li, Xiuli Yan, Haoyang Wang, Hangyu Zhou, Yuyan Li, Jian Li, Rongrong Zhang, Lu Lv, Xing‐Yao Huang, Hao Du, Tian-Shu Cao, Qing Ye, Hui John Zhao, Yan Fu, Aiping Wu, , Cheng‐Feng Qin

This paper develops VIPA mRNA therapy, which uses viral protease-initiated pyroptosis to suppress viral replication and elicit immune responses in animal models.

bioRxiv · Nov 14, 2025 · PreprintMicrobiology

Context-aware single-cell multiome approach identified cell-type specific lung cancer susceptibility genes

Erping Long, Jinhu Yin, Ju Hye Shin, Yuyan Li, Bolun Li, Alexander Kane, Harsh Patel, Xinti Sun, Cong Wang, Thong Luong, Jun Xia, Younghun Han, Jinyoung Byun, Tongwu Zhang, Zhao Wei, , Jiyeon Choi

The paper identifies cell-type specific lung cancer susceptibility genes by integrating single-cell multi-omics data with GWAS loci.

Nature Communications · Sep 12, 2024Peer-reviewedGenomics