Author

Cheng‐Feng Qin

Academy of Military Medical SciencesORCID 0000-0002-0632-2807Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Pathology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:virus· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

Hangyu ZhouiD· 2 shared Aiping WuiD· 1 shared Bowen ZhangiD· 1 shared Chunlin Zou· 1 shared Dan Li· 1 shared Hai-Tao Lu· 1 shared Hao DuiD· 1 shared Haoyang WangiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBiochemistry

Hangyu ZhouORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Novel conserved RNA structural motifs regulate genome cyclization of yellow fever virus

Yige Luo, Jingyi Zhang, Dan Li, Yi-Tian Xie, Hai-Tao Lu, Xu-Meng FENG, Yu-zhen Ding, Hangyu Zhou, Cheng‐Feng Qin, Zhongyu Liu

This study identifies a conserved RNA tertiary motif in yellow fever virus that regulates genome cyclization through interactions with the 3'-small hairpin.

bioRxiv · Oct 12, 2026 · PreprintBiochemistry

Viral protease-Initiated Pyroptosis Activator mRNA therapy as a Universal Antiviral Strategy

Lin Li, Xiuli Yan, Haoyang Wang, Hangyu Zhou, Yuyan Li, Jian Li, Rongrong Zhang, Lu Lv, Xing‐Yao Huang, Hao Du, Tian-Shu Cao, Qing Ye, Hui John Zhao, Yan Fu, Aiping Wu, , Cheng‐Feng Qin

This paper develops VIPA mRNA therapy, which uses viral protease-initiated pyroptosis to suppress viral replication and elicit immune responses in animal models.

bioRxiv · Nov 14, 2025 · PreprintMicrobiology

An artificial intelligence system reveals liquiritin inhibits SARS-CoV-2 by mimicking type I interferon

Jie Zhu, Yong‐Qiang Deng, Xin Wang, Xiao-Feng Li, Nana Zhang, Zurui Liu, Bowen Zhang, Cheng‐Feng Qin, Zhengwei Xie

The paper identifies liquiritin as an antiviral compound that inhibits SARS-CoV-2 by mimicking type I interferon, showing efficacy in cell cultures and low toxicity in mice.

bioRxiv · May 2, 2020 · PreprintSystems Biology

Integrative analysis of Zika virus genome RNA structure reveals critical determinants of viral infectivity

Pan Li, Yifan Wei, Miao Mei, Lei Tang, Lei Sun, Wenze Huang, Jianyu Zhou, Chunlin Zou, Shaojun Zhang, Cheng‐Feng Qin, Tao Jiang, Jianfeng Dai, Xu Tan, Qiangfeng Cliff Zhang

This study identifies RNA structural elements in ZIKV strains that influence infectivity through comparative in vivo analysis.

Cell Host & Microbe · Nov 21, 2018Peer-reviewedPathology