Sheyum Syed

Regulation of proteostasis by sleep through autophagy in Drosophila models of Alzheimer's Disease

This study shows that sleep modulation affects proteostasis and neurodegeneration in Drosophila Tauopathy models by altering autophagy and Tau clearance.

High-resolution, high-throughput analysis of Drosophila geotactic behavior

This paper introduces an automated system for high-resolution analysis of Drosophila geotactic behavior, enabling detailed and quantitative assessment of locomotor performance.

Context-dependent hyperactivity in syngap1a and syngap1b zebrafish autism models.

This study generates zebrafish models of SYNGAP1 disorder and shows that syngap1ab mutants exhibit context-dependent hyperactivity linked to altered arousal states.

Real time, in vivo measurement of neuronal and peripheral clocks in Drosophila melanogaster

The paper develops a method to measure circadian clocks in live Drosophila and shows that peripheral clocks can oscillate independently of the brain clock.

Daytime Color Preference in Drosophila Depends on the Circadian Clock and TRP Channels

This study shows that Drosophila's daytime color preference changes with the time of day, involving circadian clocks and TRP channels in different ways for green and blue light.

Automated analysis of internally programmed grooming behavior in Drosophila using a k-nearest neighbors classifier

The paper develops a k-nearest neighbors classifier to analyze grooming behavior in Drosophila, revealing two internal programs controlling grooming timing and duration.