Author

Tiago G. Fernandes

University of LisbonORCID 0000-0002-4651-2832Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Assay:organoid / primary culture· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alice C. Borges· 2 shared João P. CotovioiD· 2 shared Joaquim M.S. Cabral· 2 shared Adriana A. VieiraiD· 1 shared Ana Rita GomesiD· 1 shared Carina MarangaiD· 1 shared Carlos A.V. Rodrigues· 1 shared Diogo E.S. Nogueira· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBioengineering

Alice C. Borges

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Gradient-Based Regulation of Activin A Directs Multilineage Liver Organoid Development from Human Pluripotent Stem Cells

João P. Cotovio, Alice C. Borges, Diogo E.S. Nogueira, Carlos A.V. Rodrigues, Joaquim M.S. Cabral, Tiago G. Fernandes

This paper shows that adjusting Activin A levels in a 3D bioreactor system can generate liver-like structures from human stem cells, mimicking early liver development.

iScience · Oct 29, 2026Peer-reviewedBioengineering

Stem-cell modeling of cerebellar dysfunction of Angelman syndrome

Carina Maranga, Adriana A. Vieira, João Camões dos Santos, Teresa Pereira Silva, Joana Gonçalves‐Ribeiro, Karim Chébli, Miguel Casanova, Maud Borensztein, Laura Steenpaß, Sandra Henriques Vaz, Tiago G. Fernandes, Simão Teixeira da Rocha, Evguenia Bekman

This study uses stem cell-derived cerebellar organoids to model Angelman syndrome, revealing impaired development and neuronal dysfunction in cerebellar cells.

Communications Biology · Sep 28, 2026Peer-reviewedDevelopmental Biology

Transcriptomic Analysis Identifies Transient Mesendodermal State and Lineage Divergence in Human Pluripotent Stem Cell Differentiation

Alice C. Borges, Mariana A. Branco, João P. Cotovio, Ana Rita Gomes, Joana E. Saraiva, Leonilde M. Moreira, Joaquim M.S. Cabral, Domingos Henrique, Maria Margarida Diogo, Tiago G. Fernandes

bioRxiv · Aug 25, 2026 · PreprintBioengineering