Author

Karim Chébli

Centre National de la Recherche ScientifiqueORCID 0000-0002-0103-7783Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Maud BorenszteiniD· 2 shared Adriana A. VieiraiD· 1 shared Aurélie TeissandieriD· 1 shared Carina MarangaiD· 1 shared Caroline Lee· 1 shared Clara RoidoriD· 1 shared Déborah Bourc’hisiD· 1 shared Dina ZielinskiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersDevelopmental Biology

Maud BorenszteinORCID

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2 papers

Recent·Most cited

Stem-cell modeling of cerebellar dysfunction of Angelman syndrome

Carina Maranga, Adriana A. Vieira, João Camões dos Santos, Teresa Pereira Silva, Joana Gonçalves‐Ribeiro, Karim Chébli, Miguel Casanova, Maud Borensztein, Laura Steenpaß, Sandra Henriques Vaz, Tiago G. Fernandes, Simão Teixeira da Rocha, Evguenia Bekman

This study uses stem cell-derived cerebellar organoids to model Angelman syndrome, revealing impaired development and neuronal dysfunction in cerebellar cells.

Communications Biology · Sep 28, 2026Peer-reviewedDevelopmental Biology

Spatio-temporal X-linked gene reactivation and site-specific retention of epigenetic silencing in the in vivo germline.

Clara Roidor, Laurène Syx, Emmanuelle Beyne, Peggy Raynaud, Dina Zielinski, Aurélie Teissandier, Caroline Lee, Marius Walter, Nicolas Servant, Karim Chébli, Déborah Bourc’his, M. Azim Surani, Maud Borensztein

The paper maps X-linked gene reactivation and epigenetic silencing in developing PGCs, showing partial resistance to reactivation and enrichment of repressive marks.

Nature Structural & Molecular Biology · Jan 21, 2025Peer-reviewedDevelopmental Biology