David A. Dorward

Beyond Navigation - Tissue-contacting Fluorescent Lifetime Imaging reveals a pathology-linked lung cancer phenotype at the point of biopsy

The paper validates a tumour-associated phenotype identified by FLIM in lung cancer biopsies, showing it is reproducible across imaging systems and distinguishable from normal tissue.

Therapeutic signature mapping of paired direct and indirect LPS injury in an ex vivo human lung perfusion platform reveals injury-specific druggable programs

Direct and indirect LPS injury in human donor lungs produce distinct 4 h proteomic programs; signature reversal favours SYK, CDK, HDAC, JAK/STAT and PI3K/AKT/mTOR pathway modulation.

Self-supervised AI reveals a lethal discohesive phenotype in lung adenocarcinoma

This paper uses self-supervised AI to identify under-appreciated stromal morphologies in lung adenocarcinoma linked to poor prognosis, independent of current clinical schemas.