Iftach Nachman

Robust self-organization of livestock pluripotent stem cells into post-gastrulation embryo models with advanced neuronal and mesodermal structures

This study develops stem cell-based embryo models for sheep and pig, recapitulating post-gastrulation development with neuronal and mesodermal structures.

Coordination between endoderm progression and gastruloid elongation controls endodermal morphotype choice

The paper studies how coordination between endoderm progression and gastruloid elongation influences endodermal morphotype choice, identifying key drivers and interventions to reduce variability.

Emergence and patterning dynamics of mouse definitive endoderm

This study investigates the emergence and patterning dynamics of mouse definitive endoderm using in vivo and in vitro models, revealing self-sorting and Sox17 expression patterns.

Prediction and control of symmetry breaking in embryoid bodies by environment and signal integration

The paper studies how embryoid bodies integrate environmental and biochemical signals to determine symmetry breaking through the positioning of the Brachyury onset locus.