Early life stress-induced miR-708-5p regulates mood disorder-associated behavioural phenotypes in mice and is a potential diagnostic biomarker for bipolar disorder
Carlotta Gilardi, Helena Caria Martins, Alessandra Lo Bianco, Silvia Bicker, Pierre‐Luc Germain, Fridolin Groß, Ayse Özge Sungur, Theresa M. Kisko, Frederike Stein, Susanne L. Meinert, Rainer K.W. Schwarting, Markus Wöhr, Udo Dannlowski, Tilo T. J. Kircher, Gerhard M. Schratt
The paper identifies miR-708-5p as a biomarker for bipolar disorder and shows its role in regulating mood disorder-associated behaviors through targeting Nnat.
bioRxiv · Mar 14, 2024 · PreprintNeuroscience