Frederike Stein

Secure Attachment despite Childhood Maltreatment: Behavioral and Neural Correlates of Interpersonal Resilience

The paper identifies neural correlates of interpersonal resilience, finding larger gray matter volume in the left supramarginal gyrus in individuals with secure attachment despite childhood maltreatment.

Structural Brain Network Alterations in Relation to Treatment and Illness Severity in Bipolar Disorder

This study analyzes structural brain network changes in bipolar disorder, finding widespread connectivity disruptions linked to illness severity and medication use.

Childhood Maltreatment and Deviations from Normative Brain Structure: Results from 3,711 Individuals from the ENIGMA MDD and ENIGMA PTSD

The paper examines how childhood maltreatment affects brain structure in 3,711 individuals with MDD and PTSD, finding age- and sex-specific brain morphometric differences.

Neuroanatomical Correlates of Negative Symptoms in Schizophrenia

This study identifies small but consistent anatomical correlates of negative symptom dimensions in schizophrenia, linking them to prefrontal cortical thickness and limbic subcortical volumes.

Gray matter correlates of childhood maltreatment: searching for replicability in a multi-cohort brain-wide association study

This study investigates the replicability of gray matter correlates of childhood maltreatment across three cohorts and finds no significant replication after controlling for depression.

Dissecting heterogeneity in cortical thickness abnormalities in major depressive disorder: a large-scale ENIGMA MDD normative modelling study

This study uses normative modeling to analyze cortical thickness deviations in MDD patients and healthy controls, finding large overlaps and significant heterogeneity in extreme deviations across individuals.

Brain Structural Correlates of an Impending Initial Major Depressive Episode

The paper identifies neural markers of impending initial major depressive episodes by comparing converters, MDD patients, and healthy controls using voxel-wise gray matter volume analysis.

Sex differences in deep brain shape and asymmetry persist across schizophrenia and healthy individuals: A meta-analysis from the ENIGMA-Schizophrenia Working Group

Early life stress-induced miR-708-5p regulates mood disorder-associated behavioural phenotypes in mice and is a potential diagnostic biomarker for bipolar disorder

The paper identifies miR-708-5p as a biomarker for bipolar disorder and shows its role in regulating mood disorder-associated behaviors through targeting Nnat.

Connectome architecture shapes large-scale cortical alterations in schizophrenia: a worldwide ENIGMA study

This study investigates how structural brain alterations in schizophrenia relate to network architecture, finding hub susceptibility and shared epicenters across disease stages and disorders.

Interrelated effects of age and parenthood on whole-brain controllability: protective effects of parenthood in mothers

This study examines how age and parenthood affect whole-brain controllability, finding that parenthood preserves controllability in mothers but not in men.

Cross-validation for the estimation of effect size generalizability in mass-univariate brain-wide association studies

This paper investigates how cross-validation affects effect size estimation in brain-wide association studies and finds that cross-validation improves generalizability, especially in small samples.

Bipolar-associated miR-499-5p controls neuroplasticity by downregulating the Cav1.2 L-type voltage gated calcium channel subunit CACNB2

This study identifies miR-499-5p as a regulator of neuroplasticity in bipolar disorder by targeting CACNB2, leading to impaired dendritogenesis and cognitive function.

Age-dependent genetic variants associated with longitudinal changes in brain structure across the lifespan

This study identifies genetic variants linked to longitudinal brain structure changes across the lifespan using MRI data from 15,640 individuals.