Igor Nenadić

Secure Attachment despite Childhood Maltreatment: Behavioral and Neural Correlates of Interpersonal Resilience

The paper identifies neural correlates of interpersonal resilience, finding larger gray matter volume in the left supramarginal gyrus in individuals with secure attachment despite childhood maltreatment.

Childhood Maltreatment and Deviations from Normative Brain Structure: Results from 3,711 Individuals from the ENIGMA MDD and ENIGMA PTSD

The paper examines how childhood maltreatment affects brain structure in 3,711 individuals with MDD and PTSD, finding age- and sex-specific brain morphometric differences.

Gray matter correlates of childhood maltreatment: searching for replicability in a multi-cohort brain-wide association study

This study investigates the replicability of gray matter correlates of childhood maltreatment across three cohorts and finds no significant replication after controlling for depression.

Brain Structural Correlates of an Impending Initial Major Depressive Episode

The paper identifies neural markers of impending initial major depressive episodes by comparing converters, MDD patients, and healthy controls using voxel-wise gray matter volume analysis.

A generalizable normative deep autoencoder for brain morphological anomaly detection: application to the multi-site StratiBip dataset on bipolar disorder in an external validation framework.

This paper develops a deep autoencoder for detecting brain morphology anomalies in bipolar disorder using the StratiBip dataset, finding greater and more heterogeneous deviations in BD patients.

Sex differences in deep brain shape and asymmetry persist across schizophrenia and healthy individuals: A meta-analysis from the ENIGMA-Schizophrenia Working Group

Connectome architecture shapes large-scale cortical alterations in schizophrenia: a worldwide ENIGMA study

This study investigates how structural brain alterations in schizophrenia relate to network architecture, finding hub susceptibility and shared epicenters across disease stages and disorders.

Polygenic risk for schizophrenia converges on alternative polyadenylation as molecular mechanism underlying synaptic impairment

This study identifies alternative polyadenylation (APA) as a molecular mechanism linking polygenic risk for schizophrenia to synaptic impairments through functional analysis in induced neurons.

Interrelated effects of age and parenthood on whole-brain controllability: protective effects of parenthood in mothers

This study examines how age and parenthood affect whole-brain controllability, finding that parenthood preserves controllability in mothers but not in men.

Cross-validation for the estimation of effect size generalizability in mass-univariate brain-wide association studies

This paper investigates how cross-validation affects effect size estimation in brain-wide association studies and finds that cross-validation improves generalizability, especially in small samples.

Bridging Big Data: Procedures for Combining Non-equivalent Cognitive Measures from the ENIGMA Consortium

The paper demonstrates a data harmonization process for memory testing across 53 studies, reducing inter-site variance while preserving covariate effects.

Bipolar-associated miR-499-5p controls neuroplasticity by downregulating the Cav1.2 L-type voltage gated calcium channel subunit CACNB2

This study identifies miR-499-5p as a regulator of neuroplasticity in bipolar disorder by targeting CACNB2, leading to impaired dendritogenesis and cognitive function.

Genetic factors influencing a neurobiological substrate for psychiatric disorders

The paper investigates genetic factors influencing a neurobiological substrate for psychiatric disorders and finds that a common genetic variant is associated with the substrate but not directly with disease risk.

Large-scale analysis of DNA methylation identifies cellular alterations in blood from psychosis patients and molecular biomarkers of treatment-resistant schizophrenia.

This study identifies DNA methylation changes in blood samples from psychosis patients, including treatment-resistant schizophrenia, and links them to biological age, smoking, and cellular composition.

Subcortical Shape Alterations in Major Depressive Disorder: Findings from the ENIGMA Major Depressive Disorder Working Group

This study identifies subcortical shape differences in MDD patients using ENIGMA data, highlighting region-specific changes in surface area and thickness.