Author

Henrique Nogueira Pinto

Amsterdam NeuroscienceORCID 0000-0002-4686-7115Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Helga E. de VriesiD· 1 shared Joline Paulina Nugteren‐Boogaard· 1 shared Manon Karsten-van Diepen· 1 shared Michael de Kok· 1 shared N. Kok· 1 shared Nanne J. Paauw· 1 shared Nienke M. de WitiD· 1 shared Peter Lodewijk HordijkiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Helga E. de VriesORCID

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1 paper

Recent·Most cited

Pericytes and Wnt signaling induce functional blood-brain barrier phenotype in human iPSC-based model

Henrique Nogueira Pinto, N. Kok, Philipp Christoph Hauger, Manon Karsten-van Diepen, Michael de Kok, Nanne J. Paauw, Susanne M. A. van der Pol, Joline Paulina Nugteren‐Boogaard, Peter Lodewijk Hordijk, Stephanie D. Beekhuis-Hoekstra, Susan Gibbs, Nienke M. de Wit, Helga E. de Vries

This paper develops a human iPSC-based model of the blood-brain barrier by co-culturing endothelial cells with pericytes and activating Wnt/β-catenin signaling, resulting in cells with BBB-like properties and gene expression patterns.

Small Methods · Jan 28, 2026Peer-reviewedBioengineering