NeurosciencebioRxivPreprint
A multiplex platform to identify mechanisms and modulators of proteotoxicity in neurodegeneration
Samuel J. Resnick, Seema Qamar, Jenny Sheng…·Alejandro Chavez
The paper develops a multiplex reverse genetics platform to identify genetic modifiers of protein misfolding in neurodegenerative diseases and identifies DNAJB6 as a modifier of toxicity and solubility of ALS/FTD-linked RNA-binding proteins.
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