Circadian Clock Programming of Anticipatory Antiviral Immunity Gates Enteric Virus Infection Susceptibility
Temitope Oshinowo, Robert W. Maples, Mikal A. Woods Acevedo, Broc T. McCune, Hunter Dalton, Ishea Johnson, Devin Simpkins, Urbashi Basu, Chaitanya Dende, Vera L. Tarakanova, Julie K. Pfeiffer, John F. Brooks
The paper shows that the circadian clock programs antiviral immunity in the intestine, affecting susceptibility to enteric virus infection based on the time of day.
bioRxiv · May 16, 2026 · PreprintImmunology