Chaitanya Dende

This paper shows the gut microbiota regulates intestinal T cell development by directing vitamin A flux through a sequential pathway involving epithelial, myeloid, and T cells.

The paper shows that the circadian clock programs antiviral immunity in the intestine, affecting susceptibility to enteric virus infection based on the time of day.

The paper constructs a single-cell atlas of mouse intestinal immune cells across the day-night cycle, revealing circadian dynamics in gene expression and cell populations.

This study shows that the time of day affects cancer immunotherapy efficacy through a circadian clock-dependent chemokine axis in mice.

The gut microbiota enhances translation of innate barrier defense proteins through HDAC5-mediated activation of mTORC1 signaling.