Author

Vincent Antoine Chouraki

InsermORCID 0000-0002-4698-1794Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 3 Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 5 Organism:human· 5 Approach:statistical model· 5 Assay:GWAS summary statistics· 4 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:fine-mapping· 1 Approach:simulation· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Benjamin Grenier‐BoleyiD· 5 shared Sven J. van der LeeiD· 5 shared Joshua C. BisiD· 4 shared Philippe AmouyeliD· 4 shared Sudha S. SeshadriiD· 4 shared Anita L. DeStefanoiD· 3 shared Badri Narayan VardarajaniD· 3 shared Carlos CruchagaiD· 3 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersGenetics

Benjamin Grenier‐BoleyORCID

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Author profile →

5 papers

Recent·Most cited

Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants

Vincent Damotte, Sven J. van der Lee, Vincent Antoine Chouraki, Benjamin Grenier‐Boley, Jeannette M Simino, Hieab H.H. Adams, Giuseppe Tosto, Charles C. White, Natalie Terzikhan, Carlos Cruchaga, Maria J. Knol, Shuo Li, Susanna Schraen‐Maschke, Megan L. Grove, Claudia Liliana Satizábal, , Cornelia M. van Duijn

Alzheimer s & Dementia · May 18, 2021Peer-reviewedGenetics

Genome-Wide Meta-Analysis of Late-Onset Alzheimer's Disease Using Rare Variant Imputation in 324,809 Subjects Identifies Novel Rare Variant Locus NCK2: The International Genomics of Alzheimer's Project (IGAP)

Adam Christian Naj, Ganna Leonenko, Xueqiu Jian, Benjamin Grenier‐Boley, Maria Carolina Dalmasso, Céline Bellenguez, Sha Jin, Yi Zhao, Sven J. van der Lee, Rebecca Sims, Vincent Antoine Chouraki, Joshua C. Bis, Brian W. Kunkle, Peter Holmans, Yuk Yee Leung, , Gerard D. Schellenberg

medRxiv · Mar 14, 2021 · PreprintGenetic & Genomic Medicine

Analysis of shared heritability in common disorders of the brain

Verneri Anttila, Brendan K Bulik-Sullivan, Hilary K. Finucane, Raymond Kenney Walters, José Brás, Laramie E. Duncan, Valentina Escott‐Price, Guido J. Falcone, Padhraig Gormley, Rainer Malik, Nikolaos A. Patsopoulos, Stephan Ripke, Zhi Wei, Dongmei Yu, Phil Hyoun Lee, , Nicholas A. Furlotte

Genetic correlations across 25 brain disorders (215,683 cases) reveal broad psychiatric common-variant sharing, largely distinct neurological disorders, and migraine as the only significant cross-category link.

Science · Jun 21, 2018Peer-reviewedGenetics✦ In-depth digest

Meta-analysis of genetic association with diagnosed Alzheimer’s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing

B K Kunkle, Benjamin Grenier‐Boley, Rebecca Sims, Joshua C. Bis, Adam Christian Naj, Anne Boland, Maria Vronskaya, Sven J. van der Lee, Alexandre Amlie‐Wolf, Céline Bellenguez, Aura Frizzati, Vincent Antoine Chouraki, Eden R. Martin, Kristel Sleegers, Nandini Badarinarayan, , Clive Holmes

This study performs a large GWAS of Alzheimer's disease, identifies four new risk loci, and highlights pathways involving immunity, lipid metabolism, and APP/Aβ processing.

bioRxiv · Apr 5, 2018 · PreprintGenetics

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer’s disease

The International Genomics of Alzheimer's Project, Kuan-lin Huang, The Alzheimer's Disease Neuroimaging Initiative, Edoardo M. Marcora, Anna A. Pimenova, Antonio Fabio Di Narzo, Manav Kapoor, Sheng Chih Jin, Oscar Harari, Sarah E. Bertelsen, Benjamin Peter Fairfax, Jacek Czajkowski, Vincent Antoine Chouraki, Benjamin Grenier‐Boley, Céline Bellenguez, , Alison Goate

This study identifies a haplotype lowering PU.1 expression in myeloid cells that delays Alzheimer’s disease onset by affecting gene expression and function.

Nature Neuroscience · Jun 19, 2017Peer-reviewedNeuroscience