Molecular BiologyFrontiers in ImmunologyPeer-reviewed
CRISPR interference for Sequence-Specific Regulation of Fibroblast Growth Factor Receptor A in Schistosoma mansoni
Xiaofeng Du, Donald Peter McManus, Juliet D. French…·Hong You
This study applies CRISPR interference to repress SmfgfrA in Schistosoma mansoni, showing reduced transcription, protein expression, and immune response, with durable effects on parasite development and host granuloma formation.
14 citations