Author

Donald Peter McManus

QIMR Berghofer Medical Research InstituteORCID 0000-0001-6443-1449Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1

Frequent Co-Authors

Haran SivakumaraniD· 2 shared Hong YouiD· 2 shared Juliet D. FrenchiD· 2 shared Malcolm K. JonesiD· 2 shared Xiaofeng DuiD· 2 shared Conor E. FogartyiD· 1 shared Johannes U. MayeriD· 1 shared Lambros T. KoufariotisiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Haran SivakumaranORCID

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2 papers

Recent·Most cited

Molecular BiologyFrontiers in ImmunologyPeer-reviewedJan 13, 2023

CRISPR interference for Sequence-Specific Regulation of Fibroblast Growth Factor Receptor A in Schistosoma mansoni

Xiaofeng Du, Donald Peter McManus, Juliet D. French…·Hong You

This study applies CRISPR interference to repress SmfgfrA in Schistosoma mansoni, showing reduced transcription, protein expression, and immune response, with durable effects on parasite development and host granuloma formation.

14 citations

experimental assay

𝕏 PostBluesky

Molecular BiologyThe FASEB JournalPeer-reviewedDec 18, 2020

CRISPR/Cas9-mediated genome editing of Schistosoma mansoni acetylcholinesterase

Hong You, Johannes U. Mayer, Rebecca L. Johnston…·Donald Peter McManus

This paper uses CRISPR/Cas9 to edit the acetylcholinesterase gene in Schistosoma mansoni eggs, resulting in reduced AChE activity and decreased granuloma size in mice.

39 citations

mouseexperimental assay

𝕏 PostBluesky