Karl‐Herbert Schäfer

This study examines the acute and prolonged effects of Aβ on enteric neurons and intestinal motility, finding increased excitability and contractility initially, followed by structural and synaptic changes after 72 hours.

This study shows that overexpression of human alpha-synuclein in rats leads to gut microbiome dysbiosis, altered metabolites, and aging-related changes that can be modulated by antibiotics.

The paper investigates how human and bacterial amyloids affect enteric glia and smooth muscle cells, finding they trigger a pro-inflammatory response and DNA damage.

The paper identifies early gut biomarkers for Parkinson's disease in mice and humans using a transgenic model and molecular profiling.