Manuela Gries

Early Aβ-induced changes in the enteric nervous system and gut: structure, function, and motility

This study examines the acute and prolonged effects of Aβ on enteric neurons and intestinal motility, finding increased excitability and contractility initially, followed by structural and synaptic changes after 72 hours.

Enteric glia adopt an activated pro-inflammatory state in response to human and bacterial amyloids

The paper investigates how human and bacterial amyloids affect enteric glia and smooth muscle cells, finding they trigger a pro-inflammatory response and DNA damage.

Functional and molecular early enteric biomarkers for Parkinson's disease in mice and men

The paper identifies early gut biomarkers for Parkinson's disease in mice and humans using a transgenic model and molecular profiling.