Early Aβ-induced changes in the enteric nervous system and gut: structure, function, and motility
Manuela Gries, Hannah Ramona Puhl, Steven Schulte, Anne Christmann, Stephanie Rommel, Marko K. Baller, Monika Martin, Tobias Hartmann, Marcus O.W. Grimm, Karl‐Herbert Schäfer
This study examines the acute and prolonged effects of Aβ on enteric neurons and intestinal motility, finding increased excitability and contractility initially, followed by structural and synaptic changes after 72 hours.
bioRxiv · Sep 26, 2025 · PreprintNeuroscience