Author
Baylor College of MedicineORCID 0000-0002-4756-5813Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
John Hintze, Asli B. Topaktas, Thomas Daugbjerg Madsen…·Katrine T.-B. G. Schjoldager
The paper shows that O-glycans in LRP1's ligand-binding domains differentially modulate uptake of tau and amyloid beta, but not RAP or ApoE.
Zhang Yang, Muchun Niu, Chenghang Chuck Zong
SigFormer improves single-sample mutational signature decomposition by using a transformer framework, outperforming existing methods in high-noise and overcomplete settings.
Muchun Niu, Zhang Yang, Jiayi Luo…·Chenghang Chuck Zong
This study develops scNanoSeq to detect somatic mutations in single tumor cells, revealing subtype-specific evolutionary patterns and a reprogramming and critical mutation co-timing model in breast cancer.