Philip A. Kern

The paper examines transcriptional changes in adipose tissue from subacute COVID-19 and Long COVID patients, finding no persistent viral RNA but significant transcriptional remodeling in subacute cases and no consistent gene expression differences in Long COVID.

This study shows that MAM proteins and their functions in human immune cells are not altered in T2D, suggesting they are unlikely to contribute to metaflammation.

This study shows that fructose metabolism via KHK-C increases ER stress and modulates the hepatic transcriptome, contributing to NAFLD progression in both genetic and diet-induced models.

This study identifies APOE4-associated metabolic changes in brain and systemic metabolism, showing increased aerobic glycolysis and reduced oxidative metabolism in both mice and humans.