Molecular BiologyNature BiotechnologyPeer-reviewed
Multiplex gene editing by CRISPR-Cpf1 through autonomous processing of a single crRNA array
Bernd Zetsche, Matthias Heidenreich, Prarthana Mohanraju…·Feng Zhang
The paper demonstrates multiplex gene editing in mammalian cells and mouse brains using a single CRISPR array processed by Cpf1 without requiring additional factors.