Author

Matthias Heidenreich

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Feng ZhangiD· 3 shared Aviv RegeviD· 1 shared Benjamin E. DevermaniD· 1 shared Bernd Zetsche· 1 shared David A. ScottiD· 1 shared Ellen M. DeGennaroiD· 1 shared Fernando J. BustosiD· 1 shared Haley StroufiD· 1 shared

Activity by Year

2016-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Feng ZhangORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintApr 28, 2023

Removal of a genomic duplication by double-nicking CRISPR restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer.

Fernando J. Bustos, Swarna Pandian, Henny Haensgen…·Martha Constantine‐Paton

This study removes a genomic duplication in a mouse model using DN-CRISPRs, improving synaptic transmission and behavior.

2 citations

mouseexperimental assay

𝕏 PostBluesky

Molecular BiologyNature BiotechnologyPeer-reviewedFeb 1, 2017

Multiplex gene editing by CRISPR-Cpf1 through autonomous processing of a single crRNA array

Bernd Zetsche, Matthias Heidenreich, Prarthana Mohanraju…·Feng Zhang

The paper demonstrates multiplex gene editing in mammalian cells and mouse brains using a single CRISPR array processed by Cpf1 without requiring additional factors.

28 citations

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 27, 2016

Div-Seq: A single nucleus RNA-Seq method reveals dynamics of rare adult newborn neurons in the CNS

Naomi Habib, Yinqing Li, Matthias Heidenreich…·Aviv Regev

Div-Seq tracks transcriptional dynamics of rare adult newborn neurons using single nucleus RNA-Seq and EdU labeling.

DOI 10.1101/045989

𝕏 PostBluesky