Ralph Dileone

This study shows that the OX1R antagonist 1-SORA-51 reduces early binge-like feeding in mice without affecting dopamine levels.

This study shows that semaglutide reduces voluntary running and alters dopamine dynamics in the nucleus accumbens of mice, independent of food intake suppression.

This study evaluates NYX-783, an NMDAR positive allosteric modulator, in mice to assess its potential to reduce opioid withdrawal symptoms and relapse.

The paper investigates sex differences in oxycodone-taking behaviors in rats, finding that impaired reward-guided decision-making is linked to increased opioid use and addiction-related behaviors in females.

This study shows orexin signaling in GABAergic lateral habenula neurons promotes aggression and conditioned place preference, suggesting a potential therapeutic target for reducing aggressive behaviors.