Jorge Enrique Hernández González

The paper determines the cryo-EM structures of Cx32 gap junction channels reconstituted in nanodiscs, showing that phospholipids block the pore by binding to the N-terminal gating helix, contingent on sterol presence.

This study evaluates pantinin-1, a scorpion venom peptide, as an inhibitor of CHIKV nsP2 protease, showing effective inhibition with low micromolar affinity and no toxicity.