JCAD couples tight junction condensates to actin and RhoA to maintain the endothelial barrier
Kyle A. Jacobs, Yoon‐Gu Jang, Fang-Shiuan Leung, Lakyn N. Mayo, Torsten Wittmann, Jeffrey Ohmann Bush, Matthew L. Kutys
This study identifies JCAD as a scaffold that links tight junction condensates to actin and RhoA, enabling endothelial barrier adaptation to inflammation.
bioRxiv · May 21, 2026 · PreprintCell Biology