Author

Hélène Verkindt

InsermORCID 0000-0002-4776-3350Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:GWAS / association mapping· 1 Assay:metabolomics· 1

Frequent Co-Authors

François N. PattouiD· 3 shared Philippe FrogueliD· 3 shared Robert J. CaiazzoiD· 3 shared Violeta RaverdyiD· 2 shared A. Forman· 1 shared A. Fritsche· 1 shared A. Hansen· 1 shared A.M. Nielsen· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersGenetics

François N. PattouORCID

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3 papers

Recent·Most cited

Time-of-day-dependent variation of the hepatic transcriptome and metabolome is disrupted in non-alcoholic fatty liver disease patients

Manuel Johanns, Joel T. Haas, Violeta Raverdy, Jimmy Vandel, Julie Chevalier-Dubois, Loïc Guille, Bruno Derudas, Benjamin Legendre, Robert J. Caiazzo, Hélène Verkindt, Viviane Gnemmi, Emmanuelle Leteurtre, Mehdi Derhourhi, Amélie Bonnefond, Philippe Froguel, , Philippe Lefèbvre

The paper examines time-of-day-dependent transcriptome and metabolome variations in human NAFL and NASH livers, finding disruptions in rhythmic gene expression and metabolites.

bioRxiv · Apr 5, 2023 · PreprintGenomics

Meta-analysis of genome-wide DNA methylation and integrative OMICs in human skeletal muscle.

Sarah Amandine Caroline Voisin, Macsue Jacques, Shanie Landen, Nicholas R. Harvey, Larisa Margaret Haupt, Lyn Robyn Griffiths, Sofiya Gancheva, Meriem Ouni, Markus Jähnert, Kevin J. Ashton, VG Coffey, Jamie‐Lee M. Thompson, Thomas M. Doering, Anne Gabory, Claudine Junien, , Nir Eynon

The paper identifies age-related DNA methylation changes in human skeletal muscle through a meta-analysis and integrates these with transcriptomic and proteomic data, revealing enriched age-related gene expression patterns.

bioRxiv · Sep 28, 2020 · PreprintGenetics

Variation in the plasma membrane monoamine transporter (PMAT, encoded in SLC29A4) and organic cation transporter 1 (OCT1, encoded in SLC22A1) and gastrointestinal intolerance to metformin in type 2 diabetes: an IMI DIRECT study

Adem Y. Dawed, Kaixin Zhou, Nienke van Leeuwen, Anubha Mahajan, Neil Robertson, Robert Wilhelm Koivula, Petra J. M. Elders, Simone P. Rauh, Angus G. Jones, Reinhard Walter Holl, Julia Stingl, Paul W. Franks, Mark I. McCarthy, Leen M. ‘t Hart, Ewan R. Pearson, , A. Forman

This study investigates the association between genetic variants in PMAT and OCT1 transporters and metformin gastrointestinal intolerance in type 2 diabetes patients.

Diabetes Care · Mar 18, 2019Peer-reviewedGenetics