Author

Essi Laajala

Åbo Akademi UniversityORCID 0000-0002-3382-7966Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aleksandr IanevskiiD· 1 shared Anna Näätänen· 1 shared Constantine S. MitsiadesiD· 1 shared Dean A Lee· 1 shared Diana SchenkweiniD· 1 shared Diogo DiasiD· 1 shared Emma Saarinen· 1 shared Emmi JärveläiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aleksandr IanevskiORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Multimodal immunopharmacologic screens identify drugs rewiring the cancer-immune interface

Jonas Bouhlal, Emmi Jokinen, Petra Johanna Nygren, Diogo Dias, Aleksandr Ianevski, Jay Klievink, Hanna Lähteenmäki, Salomé Decombis, Hanna Duàn, Emmi Järvelä, Emma Saarinen, Anna Näätänen, Konstantin Matjusinski, Tiina Kasanen, Tiina Hannunen, , Satu M. Mustjoki

The paper identifies drugs that rewiring the cancer-immune interface by enhancing NK cell function and tumor susceptibility through multimodal screening approaches.

bioRxiv · Apr 17, 2026 · PreprintCancer Biology

Permutation-based significance analysis reduces the type 1 error rate in bisulfite sequencing data analysis of human umbilical cord blood samples

Essi Laajala, Viivi Halla-aho, Toni Grönroos, Ubaid Ullah, Mari Vähä-Mäkilä, Mirja Nurmio, Henna Kallionpää, Niina Lietzén, Juha Mykkänen, Omid Rasool, Jorma Toppari, Matej Orešič, Mikael Knip, Riikka Lund, Riitta Lahesmaa, Harri J Lähdesmäki

The paper evaluates the type 1 error rate in bisulfite sequencing analysis of umbilical cord blood samples and finds that permutation-based significance analysis reduces it, with minimal differential methylation associated with clinical variables except sex.

Epigenetics · Mar 4, 2022Peer-reviewedBioinformatics