Sanjeev Galande

This study characterizes the expression profile and establishes the conserved role of SP1 in specific processes during zebrafish development, which were previously unreported.

This study shows Satb1 interacts with cohesin and CTCF to regulate chromatin organization and gene expression during T cell development.

This study shows that SP1 enhances Wnt/β-catenin pathway effects on cell proliferation in colon development and cancer, with conserved roles in both contexts.

This study shows statins target SATB family proteins in the Wnt/β-catenin pathway, altering their expression and supporting their potential as anti-cancer agents in colorectal cancer.

The paper investigates PRDM16's role in human brain development by analyzing a patient mutation and cortical organoids, revealing its collaboration with LHX2 in gene regulation.

The paper combines promoter-capture Hi-C and Hi-C data to analyze 3D chromatin architecture in colorectal cancer, identifying dysregulated genes and histone modifications associated with tumor-suppressive programs.

This study identifies H4K20me1 as a dual regulatory histone mark in Hydra, both activating and repressing gene expression during regeneration and axis patterning.

The paper investigates the role of Satb2 in regulating zygotic genome activation and developmental transitions during vertebrate embryogenesis, showing distinct maternal and zygotic functions.

The paper identifies a novel cis regulatory element in human XIST that is regulated by CTCF and YY1 during X chromosome inactivation.

This study identifies the Hippo pathway components in Hydra and shows their role in head regeneration and bud development through YAP expression patterns and functional analysis.

The paper analyzes PDZ domain-containing proteins in prokaryotes and fungi, revealing their abundance, genomic context, and potential roles in stress response and protein synthesis.

This study identifies a direct link between SP1 and β-catenin in the Wnt signaling pathway, showing their mutual stabilization and role in target gene expression.