Émilie Courty

This study shows that the PGC-1α Gly482Ser SNP reprograms oxidative metabolism to favor energy storage, especially in females, through reduced respiratory capacity and altered metabolic responses.

This study shows that reduced NCK1 in beta cells of type 2 diabetes patients impairs the unfolded protein response and insulin secretion, with sex-specific adaptive responses observed in mice.

This study shows that fatty acids from adipocyte lipolysis stimulate insulin secretion via FFAR4 and FFAR1 receptors, highlighting adipose-islet crosstalk in metabolic regulation.

This study shows that HDAC inhibition by trichostatin A disrupts β-cell function and identity through epigenome-wide remodeling in both mouse and human β-cell models.