Developmental BiologybioRxiv
RUNX1 is required in granulocyte-monocyte progenitors to attenuate inflammatory cytokine production by neutrophils
Alexandra U. Zezulin, Daniel P. Yen, Elizabeth Howell…·Nancy A. Speck
This study shows that RUNX1 in granulocyte-monocyte progenitors limits neutrophil inflammatory cytokine production by restricting retrotransposon chromatin accessibility and type I interferon signaling.
30 citations