Sharlene Fernandes

This study models early IAV infection in alveolar organoids, revealing conserved AT2 cell responses and uninfected cell state transitions driven by inflammation.

The paper shows that the ARID1A-containing BAF complex is essential for lung development, proximal-distal axis specification, and cell fate acquisition during respiratory development.

This study shows that PRC2 maintains AT2 cell fate in the adult lung by preventing transitions to ABI and basal-like states, both in vitro and in vivo.

The paper investigates the role of Cux1 in postnatal epithelial development, finding that its loss causes transient developmental delays in multiple tissues without affecting organogenesis or regeneration.

The paper identifies PI3K signaling's role in regulating SOX9+ lung progenitor cell fate through gene regulatory networks using RNA-Seq and ATAC-Seq data.