Qi Cai

Electrical activation of piezoelectric nanoparticles reversibly opens the blood-brain barrier for minimally invasive drug delivery to targeted cortical regions.

Delta-Marches uses generative AI to simulate morphological changes between disease classes, identifying subcellular features that drive disease progression in histopathological images.

The paper develops a method to image the entire brain extracellular matrix in live tissue using a protein-reactive dye, enabling visualization of ECM structures in various brain conditions.

This paper presents a minimally invasive method to deliver peptides to the spinal cord for behavior modulation using optical stimulation of nanoparticles, demonstrating efficacy in inducing itching in mice without genetic modification.

This paper demonstrates a method to selectively open the blood-brain barrier using light-stimulated nanoparticles targeting tight junctions, enabling macromolecule and gene therapy vector delivery without neurotoxicity.