Eric T. David

This study shows ephrin-B2 promotes nociceptive plasticity and hyperalgesic priming in mice and humans through MNK-eIF4E signaling in DRG neurons.

The paper shows vinorelbine induces neuropathic pain-like state in mice through STING and MNK1 signaling linked to type I IFN induction in DRG neurons.

This paper identifies FEM-1689 as a σ2R/TMEM97 ligand that alleviates neuropathic pain by inhibiting the integrated stress response in mice and human sensory neurons.

This paper presents a minimally invasive method to deliver peptides to the spinal cord for behavior modulation using optical stimulation of nanoparticles, demonstrating efficacy in inducing itching in mice without genetic modification.

This study investigates the sex-specific role of CGRP in pain models, finding that CGRP promotes pain plasticity in female mice but has limited impact in males.