Nichole Link

The paper uses proteomic analysis and molecular dynamics simulations to uncover how ANKLE2 mutations disrupt protein interactions and phosphorylation, leading to microcephaly.

This study shows that Bx42/SNW1 regulates neural stem cell activation by controlling quiescence-to-proliferation transition, linking its loss to microcephaly.

This study identifies Imp's role in preventing seizures by regulating Syndecan mRNA in Drosophila neurons, showing that Imp loss leads to seizure behavior through Sdc dysfunction.

This study uses Drosophila to express Zika virus proteins and identifies phenotypes and host pathways disrupted by the virus during development.

This study identifies a novel adp loss-of-function mutant in Drosophila and shows it does not affect brain growth despite changes in lipid metabolism.

This study identifies ANKLE2 as a Zika virus target that regulates neuroblast asymmetric division, linking it to microcephaly and motor neuron disease through interactions with VRK1 and LLGL1.