Author

Justin K. Brache

University of WashingtonORCID 0009-0003-1631-2199Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

David R. ShermaniD· 1 shared Enming XingiD· 1 shared Hassan E. EldesoukyiD· 1 shared Kristin N. Adams· 1 shared Laarni Kendra T. AguilaiD· 1 shared Mariana Garcia· 1 shared Pui‐Kai LiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

David R. ShermanORCID

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1 paper

Recent·Most cited

MicrobiologybioRxivPreprintSep 12, 2025

The pH gradient contributes to persistence in Mycobacterium tuberculosis

Hassan E. Eldesouky, Kristin N. Adams, Justin K. Brache…·David R. Sherman

This study identifies niclosamide as a compound that induces drug tolerance in Mycobacterium tuberculosis by disrupting the pH gradient, revealing a new mechanism for persister cell formation.

DOI 10.1101/2025.09.12.675885

proteomicsexperimental assay

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