Author

Jennifer S. Thalappillil

Dana-Farber Cancer InstituteORCID 0000-0002-4860-3033Unclaimed ORCID profile · follow to get notified of new preprints

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Akhouri Kishore RaghawaniD· 1 shared Daulet AitymbayeviD· 1 shared David J. CheniD· 1 shared Haeseong ParkiD· 1 shared James M. ClearyiD· 1 shared Jun QiiD· 1 shared Khoa Tat DoaniD· 1 shared Malvina PapanastasiouiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Akhouri Kishore RaghawanORCID

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1 paper

Recent·Most cited

Chemical perturbations impacting histone acetylation governcolorectal cancer differentiation

Pornlada Likasitwatanakul, Zhixin Li, Khoa Tat Doan, Sándor Spisák, Akhouri Kishore Raghawan, Qi Liu, Priscilla Liow, Sunwoo Liv Lee, David J. Chen, Pratyusha Bala, Pranshu Sahgal, Daulet Aitymbayev, Jennifer S. Thalappillil, Malvina Papanastasiou, William Hawkins, , Nilay S. Sethi

The paper identifies HDAC1/2 inhibition as a method to promote colorectal cancer differentiation through H3K27ac gains, which can be reversed by blocking EP300.

Gastroenterology · Jul 7, 2025Peer-reviewedCancer Biology