A comparison of bioinformatics pipelines for compositional analysis of the human gut microbiome
Joanna Szopinska-Tokov, Mirjam Bloemendaal, Jos Boekhorst…·Alejandro Arias Vásquez
This paper compares five bioinformatics pipelines for analyzing 16S rRNA gene sequencing data from the gut microbiome, showing how pipeline choice affects downstream statistical results and case-control conclusions.