Author

Xunda Luo

Penn Presbyterian Medical CenterORCID 0000-0002-4880-0440Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Alexander Chan Chi HuangiD· 1 shared Amelia R. Schroeder· 1 shared Antonia RotoloiD· 1 shared Bernhard DumouliniD· 1 shared Eoin Christopher WhelaniD· 1 shared George Xu· 1 shared Humam N. KadaraiD· 1 shared Ian D. KrantziD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Alexander Chan Chi HuangORCID

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Author profile →

2 papers

Recent·Most cited

HistoSweep enables cellular-resolution tissue quality control for gigapixel images in digital pathology and spatial omics

Amelia R. Schroeder, Xiaokang Yu, Wei Li, Musu Yuan, Liran Mao, Jiyuan Yang, Nadja Sachs, Bernhard Dumoulin, George Xu, Xunda Luo, Alexander Chan Chi Huang, Katalin Suszták, Tae Hyun Hwang, Humam N. Kadara, Lars Mäegdefessel, , Mingyao Li

HistoSweep improves tissue quality control in gigapixel images by removing artifacts and preserving biologically relevant structures, enhancing analysis accuracy in digital pathology and spatial omics.

bioRxiv · Feb 2, 2026 · PreprintBioinformatics

Defining the cellular origin of seminoma by transcriptional and epigenetic mapping to the normal human germline

Keren Cheng, Yasunari Seita, Eoin Christopher Whelan, Ryo Yokomizo, Young Sun Hwang, Antonia Rotolo, Ian D. Krantz, Jill P. Ginsberg, Thomas F. Kolon, Priti Lal, Xunda Luo, Phillip Martin Pierorazio, Rebecca L. Linn, Sandra W. Ryeom, Kotaro Sasaki

This study maps seminoma transcriptomes and epigenetic features to the normal human germline trajectory, revealing similarities to primordial germ cells and identifying gene dosage effects in a patient-derived model.

Cell Reports · Jun 1, 2024Peer-reviewedDevelopmental Biology