Author

Antonia Rotolo

University of PennsylvaniaORCID 0000-0002-2891-5793Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam BaggiD· 1 shared Adam Barsouk· 1 shared Alain H. RookiD· 1 shared Alberto CarturaniD· 1 shared Andrew Evan Lee· 1 shared Antonio Imparato· 1 shared Austin YangiD· 1 shared Avery D. PoseyiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Adam BaggORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Harnessing the CD2 axis to broaden and enhance the efficacy of CAR T cell therapies

Alberto Carturan, Mathew G. Angelos, Puneeth Guruprasad, Ruchi P. Patel, Raymone Pajarillo, Andrew Evan Lee, Yunlin Zhang, Wei Xie, Jesse L. Rodriguez, Jaryse Harris, Pooja Devi, Olabisi I. Afolayan-Oloye, Jason Xu, Jonathan H. Sussman, Omar Elghawy, , Marco Ruella

This paper develops anti-CD2 CAR T-cells that overcome fratricide and improve efficacy by incorporating a PD-1:CD2 switch receptor to restore CD2 signaling.

Blood · Jan 5, 2026Peer-reviewedCancer Biology

Defining the cellular origin of seminoma by transcriptional and epigenetic mapping to the normal human germline

Keren Cheng, Yasunari Seita, Eoin Christopher Whelan, Ryo Yokomizo, Young Sun Hwang, Antonia Rotolo, Ian D. Krantz, Jill P. Ginsberg, Thomas F. Kolon, Priti Lal, Xunda Luo, Phillip Martin Pierorazio, Rebecca L. Linn, Sandra W. Ryeom, Kotaro Sasaki

This study maps seminoma transcriptomes and epigenetic features to the normal human germline trajectory, revealing similarities to primordial germ cells and identifying gene dosage effects in a patient-derived model.

Cell Reports · Jun 1, 2024Peer-reviewedDevelopmental Biology