Author

Sandra W. Ryeom

Columbia University Irving Medical CenterORCID 0000-0002-9869-4455Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Antonia RotoloiD· 1 shared Austin Choi· 1 shared Bang-Jin Kim· 1 shared Chiara CamilloiD· 1 shared Dasom Hwang· 1 shared Elena Floris· 1 shared Eoin Christopher WhelaniD· 1 shared Frank D’OvidioiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperDevelopmental Biology

Antonia RotoloORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single-nucleus multiome sequencing identifies candidate regulators of mouse gastric epithelial homeostasis

Maithê Rocha Monteiro de Barros, Katharina Bosch, Salima Soualhi, Shirin Issa Bhaloo, Thomas Chu, Tanya Hemrajani, Jin Cho, Kurtay Ozuner, Rui Fu, Heather M. Geiger, Nicolas Robine, Jade Carter, Silas Maniatis, Sandra W. Ryeom, Simon Tavaré, Karol Nowicki-Osuch

bioRxiv · Apr 27, 2026 · PreprintGenomics

Lung endothelial niche signaling governs self-renewal and fate transitions of human alveolar stem cells

Bang-Jin Kim, Dasom Hwang, Jimyung Park, Sung Joo Jang, Jaewon Kim, Chiara Camillo, Elena Floris, Austin Choi, Soomin Ryu, Frank D’Ovidio, Sandra W. Ryeom

This study identifies a lung endothelial niche that regulates human alveolar stem cell self-renewal and differentiation through MAPK and YAP signaling, showing its role in alveolar regeneration.

bioRxiv · Mar 9, 2026 · PreprintCell Biology

Defining the cellular origin of seminoma by transcriptional and epigenetic mapping to the normal human germline

Keren Cheng, Yasunari Seita, Eoin Christopher Whelan, Ryo Yokomizo, Young Sun Hwang, Antonia Rotolo, Ian D. Krantz, Jill P. Ginsberg, Thomas F. Kolon, Priti Lal, Xunda Luo, Phillip Martin Pierorazio, Rebecca L. Linn, Sandra W. Ryeom, Kotaro Sasaki

This study maps seminoma transcriptomes and epigenetic features to the normal human germline trajectory, revealing similarities to primordial germ cells and identifying gene dosage effects in a patient-derived model.

Cell Reports · Jun 1, 2024Peer-reviewedDevelopmental Biology