Author

Rebecca L. Linn

Children's Hospital of PhiladelphiaORCID 0000-0001-7671-4681Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetic & Genomic Medicine· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Ana G. CristanchoiD· 1 shared Annette Wilson· 1 shared Antonia RotoloiD· 1 shared Barbara H. ChaiyachatiiD· 1 shared Brett A. KaufmaniD· 1 shared Colin C. ConineiD· 1 shared Eoin Christopher WhelaniD· 1 shared Hakon H. HakonarsoniD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Ana G. CristanchoORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinePLoS ONEPeer-reviewedAug 6, 2025

DNA Methylation Differences Stratified by Normalized Fetal/Placental Weight Ratios Suggest Neurodevelopmental Deficits in Neonates with Congenital Heart Disease

Marin Jacobwitz, Hongbo Michael Xie, Jamie L. Catalano…·Ana G. Cristancho

The paper identifies DNA methylation differences associated with normalized fetal/placental weight ratios and links them to neurodevelopmental outcomes in neonates with congenital heart disease.

DOI 10.1371/journal.pone.0317944

humanDNA methylation

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PathologyJournal of Extracellular VesiclesPeer-reviewedApr 1, 2025

Extracellular vesicles alter trophoblast function in pregnancies complicated by COVID-19

T. N. Golden, Sneha Ramesh Mani, Rebecca L. Linn…·Rebecca Anne Simmons

This study shows that maternal extracellular vesicles from COVID-19 pregnancies alter trophoblast function, contributing to placental dysfunction.

5 citations

humanbulk RNA-seq

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Developmental BiologyCell ReportsPeer-reviewedJun 1, 2024

Defining the cellular origin of seminoma by transcriptional and epigenetic mapping to the normal human germline

Keren Cheng, Yasunari Seita, Eoin Christopher Whelan…·Kotaro Sasaki

This study maps seminoma transcriptomes and epigenetic features to the normal human germline trajectory, revealing similarities to primordial germ cells and identifying gene dosage effects in a patient-derived model.

16 citationstop 2%

humanbulk RNA-seq

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