Cell BiologybioRxivPreprint
Mechanical opening of the αE-catenin M-region gates afadin condensation in cardiomyocytes
Sabine Pokutta, Yerin Han, Korina I. Karpov…·Adam V. Kwiatkowski
The paper shows that mechanical force opens the E-catenin M-region, enabling afadin condensate formation at high-load adherens junctions in cardiomyocytes.
DOI 10.64898/2026.09.27.754825