Jeff D. Hardin

TEP-1, a glial thioester protein is required for cilia organization and intraflagellar transport in ensheathed sensory neurons

This study identifies TEP-1 as a glial thioester protein essential for cilia organization and intraflagellar transport in C. elegans, linking it to AMD and EODM pathogenesis through ciliary dysfunction.

TIAM-1 regulates polarized protrusions during dorsal intercalation in the C. elegans embryo through both its GEF and N-terminal domains

The paper investigates TIAM-1's role in regulating protrusions during dorsal intercalation in C. elegans embryos, showing its GEF domain promotes protrusions while its N-terminal domains suppress ectopic ones.

SRGP-1/srGAP and AFD-1/Afadin stabilize HMP-1/α-Catenin at rosettes to seal internalization sites following gastrulation in C. elegans

The paper identifies SRGP-1 and AFD-1 as regulators of HMP-1/α-catenin stabilization at rosettes during cleft closure in C. elegans gastrulation.

TES-1/Tes protects junctional actin networks under tension from self-injury during epidermal morphogenesis in the C. elegans embryo

This study identifies TES-1 as a protein that stabilizes junctional actin networks during cell shape changes in C. elegans embryos by preventing self-injury under tension.